SNVBox Overview

From Chasm Software Wiki

SNVBox Overview

SNVBox is a database of features precomputed for every codon in expressed human transcripts contained in the Refseq, CCDS and Ensembl databases. It allows rapid retrieval of features for very large datasets of missense variants.

Features can be retrieved from the SNVBox database using either transcript, amino acid substitution and codon position, or genomic coordinates on the GRCh37/hg19 human genome assembly.

SNVBox stores 85 features that can be broadly categorized into 3 groups:

1. Amino Acid Substitution features
2. Protein-based position-specific features
3. Exon-specific features

For a full list of available features, please refer to the SNVBox Tutorial.